Mike Nathan, MBA – Proven Serial Entrepreneur, Investor, and Startup Expert
With over two decades of entrepreneurial experience, Mike Nathan is a distinguished serial entrepreneur, investor, and business leader celebrated for turning innovative ideas into thriving enterprises. Currently, he serves as the CEO and Co-founder of Mendota Health, a nurse practitioner-led mobile wound care clinic that is revolutionizing how specialized care is delivered.
Mike’s journey began with 4.5 years of service in the U.S. Navy, where he was stationed in Yokosuka, Japan; Pearl Harbor, Hawaii; and, after 9/11, Naples, Italy. As a Boatswain’s Mate Second Class (BM2) with a Surface Warfare (SW) qualification and a search and rescue swimmer (SAR), he developed the discipline, resilience, and leadership skills that have defined his entrepreneurial success. He later enhanced his expertise by earning an MBA from Concordia University - St. Paul, equipping him with advanced business acumen that complements his real-world experience.
Mike has founded or co-founded 18 companies, including Impero, an LLC through which he runs consulting business activities, emphasizing strategy and execution for startups. Of these ventures, 9 have achieved 7-figure revenues, and 3 have surpassed 8 figures, showcasing his ability to create impactful, scalable businesses.
His ventures span healthcare, technology, consumer goods, and more, including Big Stone Capital Groupand Exit 156, two investment funds that fuel innovation and entrepreneurship. Beyond managing his own funds, Mike has helped raise tens of millions of dollars in investments for startups over the years, empowering countless founders to achieve their visions. Big Stone Capital drives transformative investments, while Exit 156 supports startups in healthcare and technology, with a focus on giving back to the community and St. John’s University, Mike’s alma mater.
Beyond founding businesses, Mike has excelled as an advisor and board member. Of the 10 board and advisory roles he has held, 6 ventures have reached 7-figure revenues under his strategic guidance. Notable contributions include Brother Justus Whiskey Co., NightWare, Bilt Ventures, and Vail Scientific, a revolutionary company poised to save millions of lives annually through early detection of sepsis. His insights and leadership have driven significant growth and innovation in these ventures. He also serves on the Augsburg University Business Advisory Council, lending his expertise to shape the next generation of business leaders.
Recognized for his achievements, Mike was named one of Twin Cities Business Magazine’s Top 100 Business People to Watch in 2025, a testament to his leadership and influence in the business community.
What distinguishes Mike is his “track record of results”—a tangible testament to his expertise as a true serial entrepreneur and investor. Unlike many who claim the title, Mike’s measurable accomplishments solidify his reputation as the go-to expert for launching, scaling, and advising companies.
At the heart of Mike’s journey is his core belief that we are here to do good things for other people and the community. He firmly believes that a well-intentioned company, powered by a small group of committed, motivated, and empowered individuals, can change the world. To Mike, a startup company represents the ultimate vehicle for making meaningful and sustainable impact, and he is dedicated to proving this belief every day through his work.
"I operate with the belief we are here to do good things for other people...and sometimes a well-intentioned company powered by motivated people is the best vehicle to have the biggest impact. My days are spending proving it."
Mike lives in Mendota Heights, Minnesota with his lovely wife Sara and two beautiful kids, Olivia and Fritz. In addition to being a loyal fan of the Minnesota Vikings he enjoys reading, playing chess, drinking whiskey, smoking cigars, making chili, swimming with the family, fighting for social justice, and laughing (mostly at himself).
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